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Thursday, February 27, 2014

Ovarian Hyperstimulation Syndrome

Ovarian Hyperstimulation Syndrome (OHSS), a serious complication of Polycystic ovarian syndrome (PCOS) can be prevented during Controlled Ovarian Hyperstimulation!

Infertility Centre has been well known in the successful treatment of infertility with PCOS.
As anovulation is the major problem with PCOS, different ovulation inducers (CC, Letrozole, Gonadoliberins, Gonadotropins) are used to recover ovulation. During the induction period scannig shows a variety of pictures of growing follicles. The sizes of follicles may vary from 10-100mm. Similarly number of follicles may also vary from 12-40 or above. When the size of the ovary increases more than 5cm, there may be a danger of OHSS.
A study was done to overcome this situation. Study duration: Jan 2011-Dec.2013
The ladies were advised to take egg white (albumin) twice or thrice daily (depending on their body weight) from the time they are induced. The number of eggs they took varied according to the number & size of the cysts during monitoring.
Serial scanning & serum estradiol monitored the follicle development. If there was >5cm of ovaries with >12 follicles with 15mm, no HCG! If there was pain in the pelvis, acetaminophene was prescribed.
There had been no cases of OHSS during these years.
The conception rate has also not been reduced. 

Endometriosis - a serious pelvic condition leads to infertility.